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1.
Chinese Journal of Lung Cancer ; (12): 17-21, 2023.
Artigo em Chinês | WPRIM | ID: wpr-971174

RESUMO

BACKGROUND@#With the extensive application of segmental lung resection in the treatment of early-stage lung cancer, how to complete segmentectomy more accurately and minimally invasively has become a research hotspot. The aim of this study is to explore the application of three-dimensional computed tomography bronchography and angiography (3D-CTBA) combined with perfusion area recognition technique in single-hole thoracoscopic complex segmentectomy.@*METHODS@#From January 2021 to January 2022, the clinical data of 112 consecutive patients undergoing single-port thoracoscopic complex segmentectomy in the Department of Thoracic Surgery, Xuanwu Hospital, Capital Medical University were retrospectively analyzed. The three-dimensional reconstruction combined with perfusion area identification technique was used to perform the operation and the clinical data were analyzed.@*RESULTS@#The average operation time was (141.1±35.4) min; the initial time of intersegmental plane display was (12.5±1.7) s; the maintenance time of intersegmental plane was (114.3±10.9) s; the intersegmental plane was clearly displayed (100%); the amount of bleeding was [10 (10, 20)] mL; the total postoperative drainage volume was (380.5±139.7) mL; the postoperative extubation time was (3.9±1.2) d; and the postoperative hospitalization time was (5.2±1.6) d. Postoperative complications occurred in 8 cases.@*CONCLUSIONS@#The advantages of 3D-CTBA combined with perfusion area recognition technique are fast, accurate and safe in identifying intersegmental boundary in single-port thoracoscopic complex segmentectomy, which could provide guidances for accuratding resection of tumors, shortening operation time and reducing surgical complications.


Assuntos
Humanos , Neoplasias Pulmonares/patologia , Broncografia , Pneumonectomia/métodos , Estudos Retrospectivos , Cirurgia Torácica Vídeoassistida/métodos , Tomografia Computadorizada por Raios X , Angiografia/métodos , Perfusão
2.
Rev. méd. Chile ; 143(2): 257-261, feb. 2015. ilus, tab
Artigo em Espanhol | LILACS | ID: lil-742578

RESUMO

Orbital emphysema is a rare complication of orbital and facial trauma, involving the sinuses and occasionally the nasal cavity. Most cases occur as a result of trauma but spontaneous orbital emphysema has been reported. Clinical manifestations are often delayed until the upper airway pressure increases as when blowing or coughing. Along with the fracture, the rupture of the underlying mucosa is essential for emphysema to manifest. We report a 29-years-old male who consulted in the emergency room due to eyelid swelling after a Valsalva maneuver, a couple of hours after suffering a facial injury secondary to a fall. In the presence of eyelid emphysema, the patient underwent craniofacial imaging studies, confirming an ethmoidal lamina papyracea fracture.


Assuntos
Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Doença Pulmonar Obstrutiva Crônica , Bronquiectasia , Broncografia , Nível de Saúde , Fenótipo , Análise de Componente Principal , Capacidade de Difusão Pulmonar , Enfisema Pulmonar , Qualidade de Vida , Curva ROC , Testes de Função Respiratória , Tomografia Computadorizada por Raios X
3.
Rev. panam. salud pública ; 37(1): 44-51, Jan. 2015. ilus, tab
Artigo em Espanhol | LILACS | ID: lil-742276

RESUMO

Objetivo. Caracterizar la tendencia de la mortalidad por cáncer en Chile según diferencias por nivel educacional en el período 2000-2010 en la población mayor de 20 años. Métodos. Cálculo de las tasas de mortalidad específica por cáncer ajustadas por edad para diferentes niveles educacionales (NE), para el período 2000-2010. Las tasas obtenidas se analizaron con un modelo de regresión de Poisson, calculando el índice de desigualdad relativa (IDR) y el índice de desigualdad de la pendiente (IDP) para cada año. Resultados. Se registraron 232 541 muertes por cáncer en el período 2000-2010. Los tipos de cáncer más frecuentes fueron de mama, estómago y vesícula biliar en mujeres; y estómago, próstata y pulmón en hombres. Las tasas de mortalidad por cáncer estandarizadas por edad fueron mayores en los NE más bajos, excepto para el de mama en mujer y el de pulmón en hombres. Las mayores diferencias se encontraron en el de vesícula biliar en mujeres y el de estómago en hombres, con mayores tasas de mortalidad específica de hasta 49 y 63 veces respectivamente, para NE bajo respecto al NE alto. Entre 2000 y 2010, las diferencias en mortalidad por NE se redujeron para todos los cánceres combinados en ambos géneros, mama en mujeres, y pulmón y estómago en hombres. Conclusiones. Durante el período estudiado, la mortalidad por cáncer en Chile estuvo fuertemente asociada al NE de la población. Esta información debe ser considerada al definir estrategias nacionales para reducir la mortalidad específica por cáncer en los grupos más desprotegidos.


Objective. Characterize the trends in mortality from cancer in Chile according to differences in educational level in the period 2000-2010 in the population over 20 years of age. Methods. Calculation of specific mortality from cancer, age-adjusted for different educational levels, for the period 2000-2010. The obtained rates were analyzed using a Poisson regression model, calculating the relative inequality index and the slope index of inequality for each year. Results. 232 541 deaths from cancer were reported in the period 2000-2010. The most frequent types were breast, stomach, and gallbladder cancer in women; and stomach, prostate, and lung cancer in men. Age-standardized mortality from cancer was greater in the lower educational levels, except for breast cancer in woman and lung cancer in men. The greatest differences were found in gallbladder cancer in women and stomach cancer in men, with specific mortality rates up to 49 and 63 times higher, respectively, for low educational levels compared to higher ones. Between 2000 and 2010, the differences in mortality by educational level were smaller for all cancers combined in both genders, for breast cancer in women, and for lung and stomach in men. Conclusions. During the period studied, mortality from cancer in Chile was strongly associated with the educational level of the population. This information should be considered when designing national strategies to reduce specific mortality from cancer in the most vulnerable groups.


Assuntos
Humanos , Broncopatias , Broncografia/métodos , Intensificação de Imagem Radiográfica/métodos , Radiografia Torácica/métodos , Tomografia Computadorizada por Raios X/métodos , Diagnóstico Diferencial
4.
Journal of Korean Medical Science ; : 591-597, 2015.
Artigo em Inglês | WPRIM | ID: wpr-99848

RESUMO

Management of cryptogenic massive hemoptysis is difficult, and conservative treatment may be inadequate to stop the hemorrhage. Surgery is not a reasonable option because there is no underlying identifiable pathology. This study aimed to investigate the radiologic findings and bronchial artery embolization outcomes in cryptogenic hemoptysis, and to compare the results with non-cryptogenic hemoptysis. We evaluated 26 patients with cryptogenic hemoptysis and 152 patients with non-cryptogenic hemoptysis. A comparison of the bronchial artery abnormalities between the cryptogenic and non-cryptogenic hemoptysis groups showed that only extravasation was more statistically significant in the cryptogenic hemoptysis group than in the non-cryptogenic hemoptysis group, while the other bronchial artery abnormalities, such as bronchial artery dilatation, hypervascularity, and bronchial-to-pulmonary shunting, showed no significant difference between groups. Involvement of the non-bronchial systemic artery was significantly greater in the non-cryptogenic hemoptysis group than in the cryptogenic hemoptysis group. While 69.2% of patients with cryptogenic hemoptysis also had hypervascularity in the contralateral bronchial arteries and/or ipsilateral bronchial artery branches other than the bleeding lobar branches, this finding was not detected in non-cryptogenic hemoptysis. Embolization was performed on all patients using polyvinyl alcohol particles of 355-500 microm. Hemoptysis ceased in all patients immediately after embolization. While recurrence of hemoptysis showed no statistically significant difference between the cryptogenic and non-cryptogenic hemoptysis groups, it was mild in cryptogenic hemoptysis in contrast to mostly severe in non-cryptogenic hemoptysis. Transarterial embolization is a safe and effective technique to manage cryptogenic hemoptysis.


Assuntos
Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Artérias Brônquicas/fisiopatologia , Broncografia , Estudos de Casos e Controles , Embolização Terapêutica , Hemoptise/diagnóstico por imagem , Hemorragia/etiologia , Recidiva , Tomografia Computadorizada por Raios X
5.
Korean Journal of Radiology ; : 648-656, 2015.
Artigo em Inglês | WPRIM | ID: wpr-83659

RESUMO

OBJECTIVE: The aim of this study was to evaluate whether the difference in the degree of collateral ventilation between canine and swine models of bronchial obstruction could be detected by using xenon-enhanced dynamic dual-energy CT. MATERIALS AND METHODS: Eight mongrel dogs and six pigs underwent dynamic dual-energy scanning of 64-slice dual-source CT at 12-second interval for 2-minute wash-in period (60% xenon) and at 24-second interval for 3-minute wash-out period with segmental bronchus occluded. Ventilation parameters of magnitude (A value), maximal slope, velocity (K value), and time-to-peak (TTP) enhancement were calculated from dynamic xenon maps using exponential function of Kety model. RESULTS: A larger difference in A value between parenchyma was observed in pigs than in dogs (absolute difference, -33.0 +/- 5.0 Hounsfield units [HU] vs. -2.8 +/- 7.1 HU, p = 0.001; normalized percentage difference, -79.8 +/- 1.8% vs. -5.4 +/- 16.4%, p = 0.0007). Mean maximal slopes in both periods in the occluded parenchyma only decreased in pigs (all p < 0.05). K values of both periods were not different (p = 0.892) in dogs. However, a significant (p = 0.027) difference was found in pigs in the wash-in period. TTP was delayed in the occluded parenchyma in pigs (p = 0.013) but not in dogs (p = 0.892). CONCLUSION: Xenon-ventilation CT allows the quantification of collateral ventilation and detection of differences between canine and swine models of bronchial obstruction.


Assuntos
Animais , Cães , Obstrução das Vias Respiratórias/diagnóstico por imagem , Broncopatias/diagnóstico por imagem , Broncografia/métodos , Modelos Animais de Doenças , Ventilação Pulmonar/fisiologia , Respiração , Suínos , Tomografia Computadorizada Espiral/métodos , Xenônio
6.
Int. j. morphol ; 31(3): 1049-1055, set. 2013. ilus
Artigo em Inglês | LILACS | ID: lil-694999

RESUMO

Anomalies of the bronchial tree may cause recurrent acute pulmonary infection and persistent obstruction symptoms. The developmental anomalies of the bronchial tree were presented mostly as case reports with an accompanying anomaly. However in this study, these anomalies were detected in multidetector computerized tomography (MDCT) images which have no reported pathology. Thoracic MDCT images of 400 patients (0-74 years old, 224 male and 176 female) were evaluated. Four tracheal bronchus (1percent) were detected. Three of them were displaced type, one of them was pig bronchus. And two accessory cardiac bronchus (0,5 percent) originated from medial wall of the intermediate bronchus were detected. According to our findings, incidence of tracheal bronchus and accessory cardiac bronchus seems to be higher in Turkish population.


Las anomalías del árbol bronquial pueden causar una infección pulmonar aguda recurrente y síntomas de obstrucción persistente. Las anomalías del desarrollo del árbol bronquial se presentan principalmente como informes de casos con una anomalía de acompañante. Sin embargo, en este estudio se detectaron estas anomalías en las imágenes de tomografía computarizada multidetector (TCMD), donde no se habían informado esta patología. Se evaluaron las imágenes de TCMD torácica de 400 pacientes (0-74 años, 224 hombres y 176 mujeres). Se detectaron cuatro bronquios traqueales (1 por ciento). Tres de ellos fueron de tipo desplazado, uno fue tipo bronquio de cerdo, y dos bronquio cardiaco accesorio (0,5 por ciento), originados de la pared medial del bronquio intermedio. De acuerdo con nuestros resultados, la incidencia de bronquio traqueal y bronquios cardiacos accesorios parecen ser mayor en la población turca.


Assuntos
Humanos , Masculino , Adolescente , Adulto , Feminino , Recém-Nascido , Lactente , Pré-Escolar , Criança , Adulto Jovem , Pessoa de Meia-Idade , Idoso de 80 Anos ou mais , Broncografia/métodos , Brônquios/anormalidades , Tomografia Computadorizada Multidetectores
7.
Artigo em Inglês | IMSEAR | ID: sea-148624

RESUMO

Fibrous tumours arising entirely within the substance of the lung are rare. We report one such rare case in whom the diagnosis was established after surgical removal.


Assuntos
Adulto , Biópsia por Agulha Fina , Broncografia/métodos , Diagnóstico Diferencial , Feminino , Humanos , Neoplasias Pulmonares/diagnóstico , Tumores Fibrosos Solitários/diagnóstico , Tomografia Computadorizada por Raios X/métodos
9.
Rev. chil. radiol ; 18(4): 170-174, 2012. ilus, graf
Artigo em Espanhol | LILACS | ID: lil-665606

RESUMO

Purpose. A) To determine types and prevalence of anatomical variants of bronchial segmentation in patients who underwent 64-section Multidetector CT (MDCT) of the chest. B) To evaluate the ability of this method as a diagnostic tool. Material and methods. We conducted a retrospective review of chest computed tomography studies of 156 adult patients, performed with Toshiba, Aquilion 64 CFX, CT Scanner Equipment, with chest volumetric acquisitions, and cuts of 0.5 mm. Images obtained allowed MPR and 3D reconstructions, along with virtual endoscopic visualization of the tracheobronchial tree, in the study period from may 2007 to may 2011, irrespective of reasons to request those examinations. Results. Eighty-nine (57 percent) of the 156 cases corresponded to male patients and 67 (43 percent) to female.patients. Fifty-two variants were found in 47 patients, since in five of them two variants were observed. The most commonly encountered variants were: variant of number (28 variants, 53 percent), of which 15 (28 percent) showed sub-superior lobar bronchus, 6 (11 percent) accessory bronchus in the left lower lobe; 5 (10 percent) isomerism of lower lobes, and 2 (4 percent) accessory bronchus in the right upper lobe. Among variations of origin (24 variants, 47 percent) we found 17 variants (33 percent) with right upper lobe bifurcation; 6 (12 percent) exhibited trifurcation of the left upper lobe bronchus, and 1 (2 percent) showed accessory tracheal bronchus. Conclusion. Anatomical variants in the tracheobronchial tree exhibited a prevalence of 33 percent in our study population. We found 52 variants in 47 patients, the most common being bifurcation of the right upper lobe bronchus, and subsuperior lobar bronchus. The study of anatomical variants, along with total anatomy of the tracheobronchial tree by 64 MDCT, irrespective of study protocol applied, can provide useful information prior to performing more invasive procedures, such as conventional bronchoscopy.


Propósito. Conocer tipos y prevalencia de las variantes anatómicas de la segmentación bronquial, en pacientes a quienes se les realizó TC de Tórax Multidetector 64 (TCMD 64). Evaluar la capacidad de este método para el diagnóstico de las mismas. Material y métodos. Se estudiaron en forma retrospectiva los estudios tomográficos que incluyeron el tórax, en 156 pacientes adultos, con tomógrafo Toshiba Aquilion 64, con adquisiciones volumétricas del tórax, cortes de 0.5 mm, obteniendo imágenes que permitieron reconstrucciones MPR, 3D y visualización endoscópica virtual traqueobronquial, en el período entre mayo de 2007 y mayo de 2011, independientemente del motivo por el cual fueron solicitados. Resultados. De los 156 estudios examinados, 89 (57 por ciento) fueron de sexo masculino y 67 (43 por ciento) femenino. En su análisis se encontraron 52 variantes, en 47 pacientes, ya que en cinco de ellos se observaron dos variantes. Entre las más frecuentes fueron: de número (28 variantes-53 por ciento), de las cuales: 15 (28 por ciento) con bronquio sub-superior; 6 (11 por ciento) bronquio accesorio en lóbulo inferior izquierdo; 5 (10 por ciento) isomerismo de lóbulos inferiores; y 2 (4 por ciento) bronquio accesorio en lóbulo superior derecho. Entre las variantes de origen (24 variantes-47 por ciento) encontramos 17 variantes (33 por ciento) con bifurcación del lóbulo superior derecho; 6 (12 por ciento) trifurcación del bronquio del lóbulo superior izquierdo; y 1 (2 por ciento) bronquio traqueal accesorio. Conclusión. Las variantes anatómicas en el árbol traqueobronquial presentaron una prevalencia en nuestra población de estudio del 33 por ciento, hallándose 52 en 47 pacientes, siendo las más frecuentes la bifurcación del lóbulo superior derecho y el bronquio subsuperior. Su estudio y el de la anatomía total del árbol traqueo-bronquial mediante TCMD 64, independientemente del protocolo de estudio empleado, puede aportar información de utilidad...


Assuntos
Feminino , Broncoscopia/métodos , Brônquios/anormalidades , Tomografia Computadorizada por Raios X/métodos , Broncografia , Brônquios/anatomia & histologia , Distribuição por Sexo , Epidemiologia Descritiva , Prevalência
10.
Yonsei Medical Journal ; : 787-792, 2011.
Artigo em Inglês | WPRIM | ID: wpr-155382

RESUMO

PURPOSE: A retrospective investigation of the clinical and radiologic features as well as the bronchoscopic appearance was carried out in patients with endobronchial aspergilloma. MATERIALS AND METHODS: Ten patients with endobronchial aspergilloma diagnosed by bronchoscopy and histological examination were identified at the Gyeongsang University Hospital of Korea, from May 2003 to May 2009. RESULTS: The patients included 9 men and 1 woman, and the age of the patients ranged from 36 to 76 (median, 58 years). The associated diseases or conditions were: previous pulmonary tuberculosis in 7 patients, lung cancer in 2 patients, pulmonary resection in 1 patient, and foreign body of the bronchus in 1 patient. The chest radiologic finding showed fibrotic changes as a consequence of previous tuberculosis infection in 6 patients and a mass-like lesion in 2 patients. Two patients had a co-existing fungus ball, and an endobronchial lesion was suspected in only 2 patients on the CT scan. The bronchoscopic appearance was a whitish to yellow necrotic mass causing bronchial obstruction in 7 patients, foreign body with adjacent granulation tissue and whitish necrotic tissue in 1 patient, whitish necrotic tissue at an anastomosis site in 1 patient, and a protruding mass with whitish necrotic tissue in 1 patient. CONCLUSION: An endobronchial aspergilloma is a rare presentation of pulmonary aspergilosis and is usually incidentally found in immunocompetent patients with underlying lung disease. It usually appears as a necrotic mass causing bronchial obstruction on bronchoscopy and can be confirmed by biopsy.


Assuntos
Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Brônquios/patologia , Broncografia , Broncoscopia , Aspergilose Pulmonar/diagnóstico , República da Coreia , Estudos Retrospectivos
11.
Artigo em Inglês | IMSEAR | ID: sea-138606

RESUMO

We present the case of a 16-year-old female patient who presented with dyspnoea, cough and noisy breathing that progressed further in hospital with the development of stridor and severe respiratory compromise requiring mechanical ventilatory support. Investigations were consistent with a diagnosis of endotracheal tuberculosis with tracheal and bronchial stenosis. Despite adequate anti-tuberculous therapy and ventilation the patient had high airway pressures, low tidal volumes and hypercapnia, which prevented weaning from mechanical ventilation. Balloon dilatation and stenting of the 4.5cm long, 2.3mm diameter stenotic tracheal segment was performed under radiological guidance. The patient was weaned successfully from the ventilator post-procedure. This report illustrates the successful management of an uncommon presentation of a common disease with modern endoscopic therapy.


Assuntos
Adolescente , Broncopatias/etiologia , Broncopatias/terapia , Broncografia , Constrição Patológica , Feminino , Humanos , Intubação Intratraqueal , Respiração Artificial , Stents , Doenças da Traqueia/complicações , Estenose Traqueal/etiologia , Estenose Traqueal/terapia , Tuberculose/complicações
12.
Chinese Journal of Lung Cancer ; (12): 424-431, 2010.
Artigo em Chinês | WPRIM | ID: wpr-323856

RESUMO

<p><b>BACKGROUND AND OBJECTIVE</b>Air bronchogram were visible in endobronchial ultrasound images of benign and malignant lesions. The aim of this study is to analyze the endobronchial ultrasound images of different characteristics of air bronchogram and clinical significance combined with pathologic section.</p><p><b>METHODS</b>From June 1, 2005 to December 30, 2008, 92 patients were found pulmonary peripheral lesions by X-ray and CT examinations, and confirmed that lesions were located lower to the segmental bronchial orifice by flexible bronchoscopy examinations. These patients were examined by radial endobronchial ultrasound probe afterwards.</p><p><b>RESULTS</b>Seventy-eight patients clarified with benign or malignant diagnosis of lesions were analyzed, among whom, 22 of 47 (46.8%) were of malignant lesion without air bronchogram, 22 patients in 25 of lesions without air bronchogram were confirmed malignant (88%), among whom, 66.7% (2/3), were of small cell lung cancer, 43.9% (18/41) were of non-small cell lung cancer, and 50% (5/10) were of poorly differentiated adenocarcinoma, no sign of air bronchogram was found in corresponding pathological sections. Among those patients with malignant lesion, 51.1% (24/47) were of irregular air bronchogram. For patients with malignant lesions, irregular air bronchogram was most commonly found in adenocarcinoma, 55.2% (16/29) of pathological sections showed signs of air bronchogram, similar sign was also found in 2 patients with moderately differentiated adenocarcinoma and 1 patient with poorly differentiated adenocarcinoma. The total percentage of patients without air bronchogram and with irregular air bronchogram was 97.9% (46/47), only one of them (with medium differentiated adenocarcinoma) showed regular air bronchogram (1.3%). 80.6% (25/31) patients with benign lesion showed regular sign of air bronchogram distributed in the shape of concentric circles, the percentage of patients without air bronchogram or with irregular air bronchogram was both 3.8% (3/31).</p><p><b>CONCLUSION</b>When there's no air bronchogram, or irregular air bronchogram sign found by endobronchial ultrasound examination, it is highly indicated that there is a malignant lesion, while there's regular sign of air bronchogram distributed in the shape of concentric circles, it is likely to be a benign lesion.</p>


Assuntos
Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Brônquios , Diagnóstico por Imagem , Broncografia , Endossonografia , Métodos , Neoplasias Pulmonares , Diagnóstico por Imagem , Patologia
13.
Rev. am. med. respir ; 9(3): 151-155, sept. 2009. ilus
Artigo em Espanhol | LILACS | ID: lil-554455

RESUMO

La ruptura bronquial es una condición rara y grave, secundaria a un traumatismo severo del tórax. Presenta una alta morbimortalidad y la mayoría de las veces requiere resolución quirúrgica. Presentamos un caso que, no habiendo sido diagnosticado inicialmente como tal, padeció complicaciones que dilataron el tratamiento correspondiente. Se realizó la colocación de stent endobronquial y sucesivas fibrobroncoscopías de control y aspiración, además de kinesia respiratoria y drenaje postural, evolucionando favorablemente.


The bronchial rupture is a rare and serious condition, secondary to a severe thoracic trauma. It often requires surgical treatment and the case fatality is high. In the case presented here the treatment was delayed because of late diagnosis and complications. The therapeutic measures included endobronchial stenting, successive control and aspiration fiberbronchoscopies, kinetic respiratory assistance and postural drainage. The evolution was favorable.


Assuntos
Humanos , Adulto , Feminino , Brônquios/lesões , Stents , Traumatismos Torácicos , Acidentes de Trânsito , Broncografia , Ruptura/cirurgia , Ruptura/diagnóstico , Ruptura
14.
J. bras. pneumol ; 33(5): 602-608, set.-out. 2007. ilus, tab
Artigo em Português | LILACS | ID: lil-467487

RESUMO

A discinesia ciliar primária (DCP), anteriormente conhecida como síndrome dos cílios imóveis, é uma doença hereditária autossômica recessiva que inclui vários padrões de defeitos em sua ultra-estrutura ciliar. Sua forma clínica mais grave é a síndrome de Kartagener (SK), a qual é encontrada em 50 por cento dos casos de DCP. A DCP causa deficiência ou mesmo estase no transporte de secreções em todo o trato respiratório, favorecendo a proliferação de vírus e bactérias. Sua incidência varia de 1:20.000 a 1:60.000. Como conseqüência, os pacientes apresentam infecções crônicas e repetidas desde a infância e geralmente são portadores de bronquite, pneumonia, hemoptise, sinusite e infertilidade. As bronquiectasias e outras infecções crônicas podem ser o resultado final das alterações irreversíveis dos brônquios, podendo progredir para cor pulmonale crônico e suas conseqüências. Somente a metade dos pacientes afetados pela DCP apresenta todos os sintomas, condição denominada SK completa; no restante, não ocorre situs inversus, condição denominada SK incompleta. O diagnóstico é feito com base no quadro clínico e confirmado por meio da microscopia eletrônica de transmissão. Como não há tratamento especifico para a DCP, recomenda-se que, tão logo seja feito o diagnóstico, as infecções secundárias sejam tratadas com antibióticos potentes e medidas profiláticas sejam adotadas. Neste trabalho, relatamos seis casos de DCP (cinco casos de SK completa e um caso de SK incompleta) e revisamos a literatura sobre o assunto, tendo como foco os aspectos diagnósticos, terapêuticos e clínicos desta doença.


Primary ciliary dyskinesia (PCD), previously known as immotile cilia syndrome, is an autosomal recessive hereditary disease that includes various patterns of ciliary ultrastructural defects. The most serious form is Kartagener syndrome (KS), which accounts for 50 percent of all cases of PCD. The incidence of PCD ranges from 1:20,000 to 1:60,000. Since PCD causes deficiency or even stasis of the transport of secretions throughout the respiratory tract, it favors the growth of viruses and bacteria. As a result, patients have lifelong chronic and recurrent infections, typically suffering from bronchitis, pneumonia, hemoptysis, sinusitis, and infertility. Bronchiectasis and other chronic conditions infections can be the end result of the irreversible bronchial alterations, leading to chronic cor pulmonale and its consequences. Only half of the patients affected by PDC present all of the symptoms, a condition designated complete KS, compared with incomplete KS, typically defined as cases in which situs inversus does not occur. The diagnosis is made clinically and confirmed through transmission electron microscopy. Since there is no specific therapy for PCD, it is recommended that, upon diagnosis, secondary infections be treated with potent antibiotics and prophylactic interventions be implemented. In this paper, we report six cases of PCD (five cases of complete KS and one case of KS) and review the related literature, focusing on the diagnostic, therapeutic and clinical aspects of this disease.


Assuntos
Adulto , Feminino , Humanos , Masculino , Síndrome de Kartagener/diagnóstico , Broncografia , Transtornos da Motilidade Ciliar/diagnóstico , Transtornos da Motilidade Ciliar/terapia , Síndrome de Kartagener/terapia , Situs Inversus , Tomografia Computadorizada por Raios X
15.
Rev. medica electron ; 29(2)mar.-abr. 2007. ilus
Artigo em Espanhol | LILACS | ID: lil-488408

RESUMO

El secuestro pulmonar forma parte de un espectro de anomalías congénitas denominadas malformaciones broncopulmonares y del intestino anterior. Una adecuada evaluación preoperatoria es aconsejable para evitar complicaciones intraoperatorias. Se caracterizaron las variantes del secuestro pulmonar a partir de conceptos actuales sobre la embriología, etiología, anatomía vascular, topografía, anatomía patológica, diagnóstico y alternativas terapéuticas.


Lung sequesters takes part of a congenital anomalies spectrum known as broncopulmonary and of the anterior intestine. It is advised an adequate presurgery evaluation to avoid intrasurgery complications. The variants of the lung sequester were characterized on the basis of the current concepts of embryology, aetiology, vascular anatomy, topography, pathologic anatomy, diagnosis and therapeutic alternatives.


Assuntos
Humanos , Sequestro Broncopulmonar , Ultrassonografia , Anormalidades do Sistema Digestório , Anormalidades do Sistema Respiratório , Broncografia/métodos
16.
The Korean Journal of Thoracic and Cardiovascular Surgery ; : 793-797, 2007.
Artigo em Coreano | WPRIM | ID: wpr-133378

RESUMO

A communicating bronchopulmonary foregut malformation (CBPFM) is a rare congenital anomaly that is characterized by a fistula between isolated respiratory tissue and the esophagus or stomach. The presence of accessory lung tissue arising from the primitive gastrointestinal tube is a common factor in the development of all forms of bronchopulmonary foregut malformations. Recurrent pneumonia associated with cystic radiographic structures is a characteristic of the condition. Further imaging studies using esophagogram, bronchography, computerized tomography, MRI, and arteriography can help in making a diagnostic evaluation. The treatment is a surgical resection of the involved lung tissue, and fistula closure with a good prognosis. We encountered a case of CBPFM, who presented with an extralobar pulmonary sequestration and bronchogenic cyst communicating with a tubular esophageal duplication that was associated with a complete left pericardial defect.


Assuntos
Angiografia , Cisto Broncogênico , Broncografia , Sequestro Broncopulmonar , Esôfago , Fístula , Pulmão , Imageamento por Ressonância Magnética , Pericárdio , Pneumonia , Prognóstico , Estômago
17.
The Korean Journal of Thoracic and Cardiovascular Surgery ; : 793-797, 2007.
Artigo em Coreano | WPRIM | ID: wpr-133375

RESUMO

A communicating bronchopulmonary foregut malformation (CBPFM) is a rare congenital anomaly that is characterized by a fistula between isolated respiratory tissue and the esophagus or stomach. The presence of accessory lung tissue arising from the primitive gastrointestinal tube is a common factor in the development of all forms of bronchopulmonary foregut malformations. Recurrent pneumonia associated with cystic radiographic structures is a characteristic of the condition. Further imaging studies using esophagogram, bronchography, computerized tomography, MRI, and arteriography can help in making a diagnostic evaluation. The treatment is a surgical resection of the involved lung tissue, and fistula closure with a good prognosis. We encountered a case of CBPFM, who presented with an extralobar pulmonary sequestration and bronchogenic cyst communicating with a tubular esophageal duplication that was associated with a complete left pericardial defect.


Assuntos
Angiografia , Cisto Broncogênico , Broncografia , Sequestro Broncopulmonar , Esôfago , Fístula , Pulmão , Imageamento por Ressonância Magnética , Pericárdio , Pneumonia , Prognóstico , Estômago
18.
Journal of the Korean Radiological Society ; : 175-177, 2006.
Artigo em Coreano | WPRIM | ID: wpr-102533

RESUMO

We report here on a case of sand aspiration in a 32-year-old man who had been accidentally buried in the deep pile of sand for four hours. Chest radiograph showed bilateral fluffy consolidations and nodular lesions with a typical 'sand bronchogram' in both lower lung zones, and these findings were more clearly visualized on the HRCT. The patient recovered completely with conservative treatment that included mechanical ventilation and postural drainage.


Assuntos
Adulto , Humanos , Broncografia , Drenagem Postural , Pulmão , Radiografia Torácica , Respiração Artificial , Dióxido de Silício
19.
Acta cir. bras ; 20(4): 311-316, July-Aug. 2005.
Artigo em Português | LILACS | ID: lil-414202

RESUMO

OBJETIVO: Estudar no implante lobar autólogo a eficiência da anastomose brônquica simples, a perfusão pulmonar e as complicacões devido a desproporcão doador/receptor. MÉTODOS: Estudou-se 15 cães submetidos à pneumonectomia esquerda, e reimplante do lobo caudal. Estudou-se a perfusão pulmonar e a anastomose brônquica, respectivamente, por cintilografia e por broncografia. O sacrifício ocorreu aproximadamente 200 dias após a cirurgia para o estudo das anastomoses e medidas de volumes e pesos pulmonares. RESULTADOS: Quatro cães foram a óbito, um por deiscência precoce de anastomose brônquica, 1 com infeccão e outros 2 por infarto pulmonar devido a oclusão da veia pulmonar no local da anastomose. A perfusão relativa do pulmão direito e esquerdo foram em média respectivamente 72,7 por cento e 27,3 por cento. A broncografia não mostrou nem estenose nem outras alteracões na anastomose brônquica. No momento do sacrifício o lobo caudal ocupava totalmente a cavidade pleural sem que houvesse evidentes desvios do mediastino. CONCLUSÕES: O estudo mostrou que a sutura brônquica término-terminal desprotegida não levou a complicacões anastomóticas. Não houve complicacões pelo fato do lobo implantado ter ocupado somente metade da cavidade pleural. As complicacões mais importantes foram o infarto pulmonar e deiscência total da parede torácica. Tanto a broncografia como a cintilografia se mostraram eficientes respectivamente, para o estudo da anastomose brônquica e da perfusão relativa do pulmão funcionante in vivo.


Assuntos
Cães , Animais , Masculino , Transplante de Pulmão , Pneumonectomia , Transplante Autólogo , Anastomose Cirúrgica , Anastomose Arteriovenosa , Broncografia , Brônquios/cirurgia , Transplante de Pulmão/efeitos adversos , Pulmão , Modelos Animais , Perfusão , Transplante Autólogo/efeitos adversos
20.
Korean Journal of Radiology ; : 107-113, 2004.
Artigo em Inglês | WPRIM | ID: wpr-182095

RESUMO

OBJECTIVE: To evaluate the high resolution computed tomography (HRCT) findings of bronchiolitis obliterans (BO) after bone marrow transplantation (BMT). MATERIALS AND METHODS: During the past three years, 11 patients were diagnosed as having BO after BMT when they developed irreversible air flow obstruction, with an FEV1 value of less than 80% of the baseline value, without any clinical evidence of infection. All 11 patients underwent HRCT, of whom eight also underwent follow-up HRCT. The HRCT images were assessed retrospectively for the presence of decreased lung attenuation, segmental or subsegmental bronchial dilatation, diminution of peripheral vascularity, centrilobular nodules, and branching linear structure on the inspiratory images. The lobar distribution of the decreased lung attenuation and bronchial dilatation was also examined. The presence of air trapping was investigated on the expiratory images. The interval changes of the HRCT findings were evaluated in those patients who had follow-up images. RESULTS: Abnormal HRCT findings were present in all cases; the most common abnormalities were decreased lung attenuation (n=11), subsegmental bronchial dilatation (n=6), diminution of peripheral vascularity (n=6), centrilobular nodules or branching linear structure (n=3), and segmental bronchial dilatation (n=3). Expiratory air trapping was noted in all patients. The decreased lung attenuation and bronchial dilatations were more frequent or extensive in the lower lobes. Interval changes were found in all patients with follow-up HRCT: increased extent of decreased lung attenuation (n=7) ; newly developed or progressed bronchial dilatation (n=4) ; and increased lung volume (n=3). CONCLUSION: HRCT scans are abnormal in patients with BO, with the most commonly observed finding being areas of decreased lung attenuation. While the HRCT findings are not specific, it is believed that their common features can assist in the diagnosis of BO in BMT recipients.


Assuntos
Adulto , Feminino , Humanos , Masculino , Transplante de Medula Óssea/efeitos adversos , Bronquiolite Obliterante/diagnóstico , Broncografia , Pulmão/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Transplante Homólogo
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